Margarita Isabel Gutiérrez Cabrera
 
 

Licenciada en Biologia, Universidad de Talca

Doctor en Ciencias mencion Investigacion y Desarrollo de Productos Bioactivos

Laboratorio de Sintesis Organica y actividad Biologica: Sintesis, purificacion y caracterizacion espectroscopica de heterociclos nitrogenados y evaluacion de su actividad biologica.


Publicaciones Relevantes Últimos 5 Años

• Molecular Docking Studies of the Antitumoral Activity and Characterization of New Chalcone. Aurelio San-Martín, Viviana Donoso, Sergio Leiva, Mitchell Bacho, Solange Núñez, Margarita Gutierrez, Juana Rovirosa, Natalia Bailón-Moscoso, Sandra Cuenca Camacho, Omar Malagón Aviles and María-Elena Cazar. Current Topics in Medicinal Chemistry, 2015, 15, 1743-1749.

• Nano-Detoxification of Organophosphate Agents by PAMAM Derivatives Esteban F. Durán-Lara, Fabian Ávila-Salas, Sebastian Galaz, Amalraj John, Adolfo Maricán, Margarita Gutiérrez, Fabiane M. Nachtigall, Fernando D. Gonzalez-Nilo and Leonardo S. Santos. J. Braz. Chem. Soc., Vol. 00, No. 00, 1-12, 2015.

• Monitoring and mechanisms of organophosphate resistance in San Jose scale, Diaspidiotus perniciosus (Hemiptera: Diaspididae). K Buzzetti, R A Chorbadjian, E Fuentes-Contreras, M Gutiérrez, JC Ríos and R Nauen. Journal of Applied Entomology doi: 10.1111/jen.12283

• Dihydroagarofuranoid Sesquiterpenes as Acetylcholinesterase Inhibitor from Celastraceae Plants: Maytenus disticha and Euonymus japonicus.Julio Alarcon, Carlos L Cespedes, Evelyn Muñoz, Cristian Balbontin, Francisco Valdes, Margarita Gutierrez, Luis Astudillo, and David Seigler. J. Agric. Food Chem. 2015, 63, 10250−10256

• Antifungal and Insecticidal properties of the Phytoconstituents of Drimys winteri (Winteraceae) growing in Chiloe Island (Chile). Muñoz O, Gutierrez M, Gonzalez R, Hammann S and Vetter W. Nat Prod Chem Res 2015, 3:182. http://dx.doi.org/10.4172/2329-6836.1000182.

• Crystal structure of (E)-2-(Benzo[d]thiazol-2-yl)-3-(pyridin-3-yl) acrylonitrile). Pedro De-La-Torre, Margarita Gutierrez, Julio Caballero, Jorge Trilleras, Luis Astudillo, Alejandro Cardenas and Ivan Brito. Zeitschrift für Kristallographie - New Crystal Structures. Volume 231, Issue 1, Pages 171–173, ISSN (Online) 2197-4578, ISSN (Print) 1433-7266, DOI: 10.1515/ncrs-2015-0073, January 2016.

• Synthesis and in silico analysis of the quantitative structure activity relationship of heteroaryl–acrylonitriles as AChE inhibitors. Pedro De-la Torre, AdrianaV.Treuer, Margarita Gutierrez, Horacio Poblete, Jans H.Alzate-Morales, JorgeTrilleras, Luis Astudillo-Saavedra, Julio Caballero. Journal of the Taiwan Institute of Chemical Engineers 59 (2016) 45–60

• Exploring coumarin potentialities: development of new enzymatic inhibitors based on the 6-methyl-3-carboxamidocoumarin scaffold A. Fonseca, M. J. Matos, J. Reis, Y. Duarte, M. Gutierrez, L. Santana, E. Uriarte and F.Borges. RSC Adv., 2016, DOI: 10.1039/C6RA05262B.

• Novel N-allyl/propargyl tetrahydroquinolines: Synthesis via Three-component Cationic Imino Diels–Alder Reaction, Binding Prediction, and Evaluation as Cholinesterase Inhibitors. Yeray A. Rodrıguez, Margarita Gutierrez, David Ramırez, Jans Alzate-Morales, Cristian C. Bernal, Fausto M. Guiza and Arnold R. Romero Bohorquez. Chem Biol Drug Des. (Aceptado) 2016.

• Efficient MW-assisted synthesis, spectroscopic characterization, X-ray and antioxidant properties of pyrazole derivatives. Efrain Polo, Jorge Trilleras, Juan Ramos, Antonio Galdamez, Jairo Quiroga, Margarita Gutierrez. Molecules. doi:10.3390/molecules21070903