Guillermo Schmeda Hirschmann
 
 


Profesor Titular

Email: schmeda@utalca.cl

Formación Profesional

BIOQUÍMICO, Universidad Nacional de Asunción, Paraguay (1978) (convalidado por la Universidad de Chile, 1990)
DR. RER. NAT., 1984 INSTITUT FÜR ORGANISCHE CHEMIE, TECHNISCHE UNIVERSITÄT BERLIN. Director de Tesis: Prof. Dr. FERDINAND BOHLMANN.

Título de la Tesis: Isolierung und Strukturaufklärung von Pflanzeninhaltsstoffen aus Compositae

Post-Doctorado

  • 1987 The World Bank, Beca Robert S. McNamara
    "Natural Products as alternative in controlling Chagas' disease vectors".

  • Belo Horizonte, Brasil. 1996 Beca Alexander von Humboldt. Kaiserslautern, Alemania Federal.
  • Publicaciones

    • Ávila, F., Theoduloz, C., López-Alarcón, C., Dorta, E., Schmeda-Hirschmann, G. (2017). Cytoprotective effect mediated by polyphenols from Chilean native berries against free radical-induced damage on AGS cells. Oxidative Medicine and Cellular Longevity (Article ID 9808520, 13 pages)

    • Schmeda-Hirschmann, G., Burgos-Edwards, A., Rojas de Arias, A., Vega G., C., Alfonso, J., Rolon, M., Brusquetti, F., Netto, F., Urra, F.A., Cárdenas, C. (2017). The Paraguayan Rhinella toad venom: Implications in the traditional medicine and proliferation of breast cancer cells. Journal of Ethnopharmacology 199, 106-118.

    • Jiménez-Aspee, F., Theoduloz, C., Vieira, M.N., Rodriguez-Werner, M.A., Schmalfuss, E., Winterhalter, P., Schmeda-Hirschmann, G. (2016). Phenolics from the Patagonian currants Ribes spp.: isolation, characterization and cytoprotective effect in AGS cells. Journal of Functional Foods 26, 11-26.

    • Cattaneo, F., Costamagna M.S., Zampini I.C., Sayago, J., Alberto M.R., Chamorro V., Pazos A., Thomas-Valdés, S., Schmeda-Hirschmann, G., Isla, M.I. (2016). Flour from Prosopis alba cotyledons: a natural source of nutrient and bioactive phytochemicals. Food Chemistry 208, 89-96.

    • Nina, V., Quispe, C., Jimenez-Aspee, F., Theoduloz, C., Leiva, E., Feresin, G.E., Lima, B., Schmeda-Hirschmann, G. (2015). Antibacterial activity, antioxidant effect and chemical composition of propolis from Región del Maule, central Chile. Molecules 20, 18144-18167.

    • Pérez, M.J., Cuello, A.S., Zampini, I.C., Ordoñez, R.M., Alberto, M.R., Quispe, C., Schmeda-Hirschmann, G., Isla, M.I. (2014). Polyphenolic compounds and anthocyanin content of Prosopis nigra and Prosopis alba pods flour and their antioxidant and anti-inflammatory capacity. Food Research International 64, 762-771

    • Schmeda-Hirschmann, G., Quispe, C., Theoduloz, C., Teixeira de Sousa, P., Parizotto, C. (2014). Antiproliferative activity and new argininyl bufadienolide esters from the “Cururú” toad Rhinella (Bufo) schneideri. Journal of Ethnopharmacology 155, 1076-1085.

    • Simirgiotis, M.J., Bórquez, J., Schmeda-Hirschmann, G. (2013). Antioxidant capacity, polyphenolic content and tandem HPLC-DAD-ESI/MS profiling of phenolic compounds from the South American berries Luma apiculata and Luma chequén. Food Chemistry 139, 289-299.

    • Simirgiotis, M., Schmeda-Hirschmann, G., Borquez, J., Kennelly. E. (2013). The Passiflora tripartita (banana passion) fruit: a source of bioactive flavonoid C-glycosides isolated by HSCCC and characterized by HPLC–DAD–ESI/MS/MS. Molecules 18, 1672-1692.

    • Simirgiotis, M.J., Silva, M., Becerra, J., Schmeda-Hirschmann, G. (2012). Direct characterization of phenolic antioxidants in infusions from four medicinal Mapuche plants by liquid chromatography with diode array detection (HPLC-DAD) and electrospray ionization tandem mass spectrometry (HPLC-ESI-MS). Food Chemistry 131, 318-327.

    Link ResearchGate

    Editor Asociado

    Journal of Ethnopharmacology (Elsevier);

    Participación en Comités Editoriales:

    Evidence-Based Complementary and Alternative Medicine
    http://www.hindawi.com/journals/ecam/editors/

    Chinese Herbal Medicines (CHM)
    Phytopharmacology
    http://phytopharmacology.inforesights.com/editorial_board.html

    Frontiers in Plant Metabolism and Chemodiversity

    http://www.frontiersin.org/Plant_Metabolism_and_Chemodiversity/editorialboard

    Proyectos En Ejecución (En Chile)

  • FONDECYT 1120096. Metabolomics of Chilean native fruits (Investigador Responsable)

  • Listado de proyectos FONDECYT como Investigador Principal y Co-investigador:
    http://ri.conicyt.cl/575/propertyvalue-14197.html
  • Líneas de investigación

    Química y bioactividad de plantas alimenticias y medicinales sudamericanas. Perfiles de metabolitos bioactivos en matrices agroforestales. Alimentos tradicionales sudamericanos, nutracéuticos y recursos fitogenéticos nativos. Etnofarmacología y etnobotánica. Relaciones estructura-actividad en compuestos bioactivos. Mecanismos de acción de productos naturales/nutracéuticos empleando cultivos celulares.

    Por favor, ver en publicaciones:
    www.researchgate.net/profile/Guillermo_Schmeda-Hirschmann